ATRP와 클릭화학을 통한 core-crosslinked 고분자 마이셀의 합성
- Abstract
- Core cross-linked (CCL) polymeric micelles were prepared by azide-alkyne click chemistry. Poly(ethylene glycol)-b-poly(glycidyl methacrylate) (PEG-b-PGMA) block copolymers were prepared by the Atom Transfer Radical Polymerization (ATRP) and the PGMA parts were subsequently functionalized with azido groups. The CCL micelles of the azido-functional PEG-b-PGMA-N3 were prepared using dipropargyl 3,3’-dithiodipropionate as a disulfide-containing cross-linking agent. The block copolymers and CCL micelles were characterized by gel permeation chromatography(GPC), fourier transform infrared spectroscopy(FT-IR), nuclear magnetic resonance(NMR), transmission electron microscopy(TEM), and dynamic light scattering(DLS) analyses.
- Issued Date
- 2016
- Awarded Date
- 2016. 2
- Type
- Dissertation
- Keyword
- ATRP CCL micelle click chemistry
- Publisher
- 부경대학교 대학원
- Affiliation
- 부경대학교 대학원
- Department
- 대학원 융합디스플레이공학과
- Advisor
- 임권택
- Table Of Contents
- Ⅰ. 서론 ···················································································· 1
Ⅱ. 이론적 배경 ········································································· 3
2.1 블록공중합체 ········································································· 3
2.2. 마이셀 ················································································ 5
가. 고분자 마이셀 ········································································ 5
나. 가교화된 마이셀 ······································································ 7
2.3. Atom Transfer Radical Polymerization (ATRP) ··························· 8
가. 리빙 라디칼 중합 (Living Radical Polymerization) ·························· 8
나. ATRP ················································································· 11
2.4. Click chemistry ·································································· 13
Ⅲ. 실험 ·················································································· 16
3.1. 시약 ·················································································· 16
3.2. PEG-Br 거대개시제의 합성 ···················································· 16
3.3. PEG-b-PGMA 블록공중합체의 합성 ········································· 17
3.4. PEG-b-PGMA-N 블록공중합체의 합성 ···································· 18
3.5. 코어가 가교된 (CCL) 마이셀의 합성 ········································· 18
3.6. 분석장치 및 분석방법 ···························································· 19
Ⅳ. 결과 및 고찰 ······································································ 20
4.1. 블록공중합체의 합성 ····························································· 20
4.2. PEO-b-PGMA 공중합체의 ring opening ··································· 26
4.3. core cross-linked 마이셀의 합성 ············································ 29
Ⅴ. 결론 ·················································································· 37
Ⅵ. 참고문헌 ············································································ 38
- Degree
- Master
- Appears in Collections:
- 대학원 > 융합디스플레이공학과
- Files in This Item:
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ATRP와 클릭화학을 통한 core-crosslinked 고분자 마이셀의 합성.pdf
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