Design of portable high intensity focused ultrasound system and ultrasonic pulser-receiver

Abstract

Therapeutic ultrasound at high energy is absolutely useful in non-invasive surgical applications such as prostate cancer, brain tumor and other diseases. It is studied in the enhancement of drug delivery and targeted chemotherapy. The circuit was designed with a very low output impedance that allows to transferring the voltage from battery supply to transducer without using impedance matching circuitry. The device produces therapeutic acoustical energy waves at 100V peak-to-peak supply voltage and delivers acoustic power outputs (up to 40W) across 2MHz ultrasound transducer. The circuit was used in ex-vivo experiment with the goal of 60 degree Celsius. Another ultrasound application system is ultrasonic pulser-receiver. Ultrasonic pulser-receiver is a complete instrument well designed for ultrasound imaging and general purpose ultrasound testing such as NDT (Nondestructive Testing) application. The pulser can be easily configured by manual analog control with wide adjustable voltage range (12V-100V) and narrow pulse duration along with very small rising time. The receiver is available in 100MHz bandwidth included ultra-low noise 28dB amplifier that provide +/- 1 peak-to-peak of echo signal. The device also was designed portable, light-weight and small size with a stand-alone enclosure for long-time use.