Fe(0)촉매를 이용한 Dienyne의 분자내 〔4＋2〕고리화 첨가반응에 관한 연구

Abstract

The intramolecular formal iron-catalyzed 〔4+2〕 cycloaddition reaction of acetylenic dienes to produce bicyclic products has been investigated. With a typical iron(0) catalyst, prepared by the reduction of Fe(acac)3 with Et3Al in the presence of bipyridine ligand, the (E,E)-4, 4-dicarboethoxy-1-phenyldeca-1-yne-6, 8-diene proceeded competing via intramolecular carbocylization and bimolecular cycloaddition. However, under the similar condition except the chiral ligand, the 4, 4-dimethly〔 -3-(tert-mutyldimethylsiloxy)-1-pheny〕-6, 8-decadien-1-yen yielded exclusively bicyclic diene product(yield 86%).