카드뮴-아스코르빈산의 혼합사료 급이에 따른 강도다리, Platichthys stella의 독성 및 해독효과

Abstract

In oder to determine the detoxification effect of Vitamin C derivative, L-Ascorbyl-2-monophospate(AMP), Starry flounder, Platichthys stellatus (mean length 19.87±0.21 cm, and mean weight 139.47±1.41 g) were exposed for 4 weeks with the different levels of dietary cadmium at 0, 40, 80 mg/kg and 240 mg/L and L-Ascorbyl-2-monophospate at 0, 200, 400, 800 mg/kg. The accumulation of cadmium significantly increased in organs of P. stellatus and the highest accumulation was observed in intestinal tissues. The growth performance of P. stellatus was considerably decreased. In hematological parameters, the RBC count, hematocrit, and hemoglobin were significantly decreased, and the notable alterations in plasma components such as calcium, magnesium, glucose, cholesterol, GOT, and GPT were observed. The dietary Cd exposure affected the hematological parameters and growth performance of P. stellatus, and the high concentration of AMP supplementation was substantially effective to attenuate the toxic effects of the Cd exporsure. In antioxidant, The SOD, CAT, GST activity and GSH level of liver and gill were considerably elevated by the dietary Cd exposure. As a vitamin C derivative, the high levels of AMP supplementation attenuated the increase in the SOD, CAT, GST activity and GSH level.