톱니모자반(Sargassum serratifolium)의 항산화 효과 증대를 위한 추출공정 최적화

Abstract

Sargassum serratifolium has been known to contain a high level of meroterpenoids as antioxidatnt components. The optimal condition of extraction temperature and time was obtained for the maximum extraction of yield, antioxidant activity and phenolic content from Sargassum serratifolium by using response surface methodology (RSM). Independent variables include extraction temperature (30~70℃) and time (12~36 hr), dependent variables include yield, DPPH radical-scavenging activity and total phenolic content. The extraction temperature and time significantly influenced the yield, DPPH radical-scavenging activity and total phenolic content. As the extraction temperature and time increased, yield increased, but DPPH radical-scavenging activity and total phenolic content decreased. The optimal condition obtained by RSM is 54℃ extraction temperature, 7 hr extraction time. In this condition, the yield was 8.2%, DPPH radical-scavenging activity was 60% and total phenolic content was predicted to be 163 mg GAE/g. These results of this study suggest useful information in the manufacturing process for developing Sargassum serratifolium extract as food and cosmetic ingredients.