Scanning Acoustic Microscope For Biological And Industrial Applications
- Alternative Title
- 생물학 및 산업 응용 분야를 위한 스캐닝 음향 현미경
- Abstract
- Scanning acoustic microscope (SAM) by using single-element transducers has long been in favor of many applications due to its simple, compact, and cost effective features. In spite of the technology has reached to mature level, some practical applications still remain challenges in terms of automation. In this dissertation, we present several applications of SAM using single-element transducers in different fields.
In tissue characterization by SAM using the speed of sound of the tissue, reference phase extraction plays a critical role in practical aspect. In the section, we constructed a circumstance which fails the reference phase obtaining and proposed a new method to improve the work. We conducted tumor discrimination in such circumstance and compared with the conventional approach. The result from tumor discrimination by SAM was also underpinned by Hematoxylin and eosin staining.
Temporal resolution is considering a significant obstacle of SAM using single-element transducers. In the chapter 3, we proposed a novelty scanning mechanism to take advantage of using single-element transducers. We applied the scanner with quadruple-channel and dual-channel to SAM and photoacoustic microscope, respectively. The applications of the scanner in vivo and industry were also conducted.
In the chapter 4, an automatic and flexible SAM using angular transducers for non-destructive testing of welding steel cylinders was constructed. The angular transducers provide a side view to the vertical cross-section of the cylinders. In the conventional approaches, the welding sections are manually inspected by high-skill operators. To perform in-line inspection with improved reliability and high flexibility, a system with cooperation between articulated robots was proposed. For sample distribution, an industrial robot was deployed. A cooperative robot which attached the ultrasonic probes scan along a rotating cylinder during data acquisition. Four samples which divided into transmission mode and echo mode, were designed for this demonstration. A-scan, B-scan, and C-scan were achieved and displayed in real-time imaging. The acquired data is analyzed, assessed by configurable parameters on the inspection software. This system was designed in module which can be integrated to production lines.
- Issued Date
- 2022
- Awarded Date
- 2022. 2
- Type
- Dissertation
- Publisher
- 부경대학교
- Affiliation
- Pukyong National University, Graduate school
- Department
- 대학원 4차산업융합바이오닉스공학과
- Advisor
- Junghwan Oh
- Table Of Contents
- Chapter 1. Introduction 1
1.1 Background 1
1.2 Motivation 3
1.3 Overview 4
Chapter 2. The Reference Phase Correction for the Fluctuated Scanning Lines and the Slope of the Stage in Tissue Characterization by Scanning Acoustic Microscope 6
2.1 Introduction 6
2.2 Materials and Methods 9
2.2.1 Hypothetical Calculation 9
2.2.2 Experiment setup 13
2.2.3 Tissue Preparation 16
2.2.4 Practical Calculation 17
2.2.5 Statistical Analysis 22
2.3 Results and Discussions 22
2.4 Chapter 3 conclusions 28
Chapter 3. Slider-crank scanning mechanism for dual-channel photoacoustic microscopy and quadruple-channel scanning acoustic microscopy 29
3.1 Introduction 29
3.2 Materials and methods 32
3.2.1 The slider-crank mechanism 32
3.2.2 The configuration of the slider-crank systems 34
3.3 Results 36
3.3.1 Resolution 36
3.3.2 In vivo enlarged photoacoustic imaging of a mouse sagittal 40
3.3.3 In vivo human B-mode scanning acoustic microscopic imaging 41
3.3.4 In industry chip inspection by scanning acoustic microscopic system 42
3.4 Discussion 43
3.5 Chapter 3 conclusions 44
Chapter 4. Automated system for ultrasonic testing of steel cylinders 45
4.1 Introduction 45
4.2 System overview 47
4.2.1 Industrial robot 48
4.2.2 Cooperative robot 49
4.2.3 The Sample slots 50
4.2.4 The rolling unit 51
4.2.5 The ultrasonic unit 52
4.2.6 Watering unit 53
4.2.7 Controllers 55
4.3 Working procedure overview 57
4.3.1 System connection diagram 57
4.3.2 The system work flow 58
4.4 Acoustic scanning principle 60
4.4.1 Angular transducers 60
4.4.2 Roller-sample transmission ratio 66
4.4.3 Data acquisition 69
4.5 Inspection software 75
4.5.1 Color bar control panel 76
4.5.2 Sample slots configuration 77
4.5.3 Pulser/receiver control panel 77
4.5.4 Result list 78
4.6 Results and discussion 80
4.7 Chapter 4 conclusions 86
Chapter 5. Conclusions 87
Reference 88
- Degree
- Doctor
- Appears in Collections:
- 대학원 > 4차산업융합바이오닉스공학과
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