납 (Pb) 노출에 따른 참돔 Pagrus major의 생체 축적 및 산화효소활성의 변화

Abstract

Lead, a group IVA element in the periodic table, is not required for normal physiology in plants or animals and is potentially toxic. It is a naturally occuring metal present in the earth’s crust, rock, soil, and water. Lead inflow aquatic environmentals by a number of pathways. The present, most waterborne lead derives from human activities. Lead is common heavy metal pollutants of the environment. In waterborne lead, which causes to physiological effect, oxidative stress and bioaccumulation. The objective of this study was to investigate the effects of 4 weeks exposure to lead (0, 25, 50, 100, 200, 400㎍/L) on growth, hematology parameters, antioxidative response and bioaccumulation of red seabream, Pagrus major. Bioaccumulation of lead in all the examined tissues showed a similar behavior, except for muscle, and accumulation quantity of lead for 4weeks had much gill, intestine, liver, spleen, kidney, muscle in descending order. Generally, compared to control, bioaccumulation was significantly increased over 100㎍ Pb/L concentration. Growth of red seabream was decreased, because daily length gain was decreased over 50㎍ Pb/L concentration and daily weight gain was decreased over 50㎍ Pb/L concentration. In hematological parameters, Pb reduced RBC count, hematocrit and hemoglobin. In inorganic substance of serum parameters, calcium and magnesium were elevated. In organic substance, Triglyceride and glucose were changed, however total protein was not. GOT and GPT were increased entire section and significantly changed at high concentration. SOD and GST activity of antioxidative enzyme were vitality at high concentration remarkably in liver and gill. And Pb induced significantly increased GSH in liver.