트레드밀 훈련과 흑마늘 투여가 흰쥐의 코티졸 호르몬과 염증인자에 미치는 영향

Abstract

The purpose of this study was to investigate the combined effects of treadmill training and black garlic intake on cortisol hormone, CK, CK-MB, LDH, troponin T and myoglobin levels in rat. Forty-eight male Sprague-Dawley rats, 4weeks old, were used in this experiments. Experimental groups were divided into four groups: control group (CG, n=12), training group (TG, n=12), black garlic intake group (GG, n=12), and training with black garlic intake group (TGG, n=12). Treadmill training was performed through a treadmill running program in resting periods (7∼21 m/min, 0° grade, 20∼30 min/day, 5 day/week) and also they were put exercise stress in the stress periods(30 m/min, 5° grade, 30 min) and these rats were given 260mg/kg black garlic for 5 weeks according to the references. The results were as follows

1. Treadmill training program periods

1) In the cortisol hormone levels, there was no significant difference among TG, GG, TGG, and CG group after five weeks treadmill training program. 2) In the CK hormone levels, there was slightly increased in TG (p< .01) and TGG compare to CG except GG after five weeks treadmill training program. 3) In the CK-MB levels, there was slightly increased in TG (p< .01) and TGG compare to CG except GG after five weeks treadmill training program. 4) In the LDH levels, there was slightly increased in TG (p< .01) and TGG, compare to CG except GG after five weeks treadmill training program. 5) In the troponin T levels, there was slightly increased in GG (p< .05) after five weeks treadmill training program, however TG and TGG didn’t change. 6) In the myoglobin levels, there was no significant difference among TG, GG, TGG compare to CG after five weeks treadmill training program.

2. Exercise stress periods

1) In the exercise stress response, cortisol hormone level was slightly increased in CG (p< .01) and GG (p< .05), however, there was no significant difference with TG and TGG. 2) In the CK levels, there was slightly increased with a CG (p< .01), GG (p< .05) and TGG (p< .01), however, there was no significant difference with TG. 3) In the CK-MB levels, there was slightly increased in CG (p< .01), and GG (p< .05), and there was slightly decreased in TG(p< .05). however, there was no significant difference with TGG.

4) In the LDH levels, there was slightly increased in CG, TG, GG, and TGG (p< .05). 5) In the troponin T levels, there was slightly increased in CG (p< .05), however, there was no significant difference with TG, GG, and TGG. 6) In the myoglobin levels, there was slightly increased in CG (p< .01), however, there was no significant difference with TG, GG, and TGG.

From the results, we can say that the combined effects of treadmill training and black garlic intake had a good effect on muscle inflammatory variables such as CK, CK-MB, LDH, troponin T and myoglobin including cortisol hormone in resting and exercise stress periods.